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GLP-1 RAs: From Rare to Routine GLP-1 RA are increasingly prescribed and recognized as therapeutics for metabolic health and cardiovascular health, with benefits that extend beyond weight loss

These medicines mimic the action of a naturally occurring hormone called GLP-1, which is produced in the intestines in response to food intake

BMJ (2017) 359:j4849

Clinical trials show that patients using these medications experience slower gastric transit times by 2040% compared to baseline

Some patients who need continuous treatments may prefer oral products since they minimize needle phobia, hassle associated with injections, storage difficulties, and injection fatigue that comes with GLP-1 injectables

These peripheral actions occur without requiring the medication to enter the brain