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Bossart M, Wagner M, Elvert R et al (2022) Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

The popular weight-loss drug Wegovy, which has helped millions of Americans shed pounds, can now be used to reduce the risk of stroke, heart attacks and other serious cardiovascular problems in patients who are overweight or who have obesity, federal regulators said Friday

The financialized nature of the pharmaceutical industry exacerbates these challenges

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Many other factors, such as gut hormones, bile acids, microbiota, and sympathetic drive, may also contribute to VSG-induced bone loss

Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials