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42,43 Several GLP-1R agonists, including exenatide, liraglutide, and semaglutide, have been used in NASH clinical research

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For example, protein intakes of up to 1.5 g/kg/day have been suggested for this population 28

In December 2020, the US Food and Drug Administration (FDA) approved labeling changes stating that Januvia (sitagliptin), Janumet (sitagliptin and metformin hydrochloride), and Janumet XR (sitagliptin and metformin hydrochloride extended-release) are not proven to improve glycemic (blood sugar) control in children aged 10 to 17 with type 2 diabetes

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10.1038/nm919 [DOI] [PubMed] [Google Scholar] Edholm T., Degerblad M., Gryback P., Hilsted L., Holst J