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GLP-1 drugs are a class of medications used to treat obesity and type 2 diabetes that include semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound)

The long elimination half-life of 25-68 hours further supports convenient once-daily dosing

PlexusDx providers maintain contact with patients throughout treatment, adjust doses based on tolerance and results, and screen for side effects like nausea, injection-site reactions, or gastrointestinal changes

Gold S, Freid H, Shalom E, et al

That can lead to nutrient shortfalls

While some indicate an improvement in parameters associated with depression (98), others show an increased risk, especially after longer periods of drug exposure and with the newer drugs with a longer half-life (99, 100), though some other studies indicate a higher risk with liraglutide compared to semaglutide (which in that particular study was associated with reduced risk for psychiatric events) (101)