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The reason gut flora convert berberine into DHB is because, unlike berberine, DHB can pass through intestinal tissue, which enables it to reach the bloodstream

For this story, Fortune used generative AI to help with an initial draft

By hitchhiking on albumin, retatrutide avoids rapid renal clearance and proteolytic destruction, which is how Lilly gets a once-weekly injection out of a peptide that would otherwise disappear in hours
