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Patients who required invasive management (surgery, radiologic or endoscopic intervention) or died from postoperative complication where issued as severe morbidity (grade IIIV) 45

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doi: 10.1073/pnas.120069197

doi: 10.1056/NEJMoa1911303 63 PackerMAnkerSDButlerJFilippatosGPocockSJCarsonPet al
