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This review article discusses the potential antidepressant effects of GLP-1RAs, especially in the context of their action on the processes related to neuroprotection, inflammation, stress response, energy metabolism, gut-brain crosstalk and the stability of the gut microbiota

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A synthesis method and peptide resin technology, applied in the field of semaglutide synthesis, can solve the problems of difficult removal of peptide impurities, unfavorable purification, difficult coupling, etc., and achieve the effect of facilitating industrial scale-up and improving the purity of crude peptides