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doi: 10.1161/jaha.113.000438 42 LyCLCuzzoneDAKataruRPMehraraBJ

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Involvement of FoxO1 in the effects of follicle-stimulating hormone on Inhibition of apoptosis in mouse granulosa cells
In 2023 the firm abandoned development of lotiglipron after trial participants showed elevated liver enzymes, and the same year discontinued a twice-daily danuglipron dosing regime after almost three quarters of treated patients experienced nausea, while almost a half developed vomiting and a quarter diarrhoea

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Although, in 2017, the FDA approved Semaglutide for treating type 2 diabetes under the name Wegovy
