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While the GLP-1 response to the starch meal did not correlate with gastric emptying time, significant interindividual variability was observed in GLP-1 responses to intraduodenal nutrients, with the gastric emptying rate partially influenced by GLP-1 responsiveness to glucose [120]

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The advent of these medicines represents a tipping point in the treatment of obesity, its complications, and related comorbidities, the WHO officials write

JCI Insight 5(17):e140532 Killion EA, Wang J, Yie J, Shi SD, Bates D, Min X et al (2018) Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models

(2025, November 21)

Preservation of Muscle and Bone Mass The adverse effects of weight reduction on muscle and bone massparticularly among individuals with insufficient physical activity or protein intake or at older ages 63,158 have highlighted the interrelated priorities to preserve muscle mass, muscle quality, bone mass, and physical function