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The American Diabetes Association now recommends GLP-1 RAs for patients with established ASCVD regardless of their A1C and regardless of if the patient is taking metformin, the historically first line medication for T2DM [38]

Tirzepatide is a revolutionary medication initially developed to treat type 2 diabetes

Effects on weight In the SURPASS programme, change in weight was a prespecified secondary outcome

The right choice depends on your clinical eligibility, budget, risk tolerance, and your Provider's recommendation - it's a conversation to have during your consultation, not one that can be made from a review article

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