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efferent renal nerves to regulation of GLP-1 mediated diuresis and natriuresis in HF, either total renal denervation with surgical cutting of the renal nerves or a selective afferent renal denervation with periaxonal application of capsaicin were performed as demonstrated previously [24,25,26]

The proteolytic stability to NEP 24.11 could predict mostly the results in mouse plasma

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