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however, it negatively affected the fetal weight, yet it was considered negligible due to liraglutides known effect of suppressing appetite ( As GLP-1 agonists have garnered attention for management of obesity due to their effect on reducing insulin sensitivity, they are now being considered a therapeutic option for the treatment of PCOS (polycystic ovarian syndrome), one of the most common causes of subfertility, diagnosed via Rotterdams criteria: oligomenorrhea, hyperandrogenism and polycystic ovaries ( A comparative study conducted between GLP-1RA + Metformin in contrast to cyproterone acetate/ethinylestradiol + Metformin in overweight PCOS women, conducted over a period of 12 weeks, implied that GLP-1 RA+Metformin was superior in reducing the waist circumferences as well as preserving blood sugar levels by improved HbA1c levels and regulating menstrual cycle

Researchers investigating isolated GLP-1 signaling may prefer a GLP-1 receptor agonist

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The answer is that people with type 1 diabetes are not exempt from other illnesses or causes of ill health

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This genetic heterogeneity explains why some patients benefit substantially while others experience limited response