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The 0.25mg semaglutide starting dose typically produces modest initial weight loss of 2-4 pounds over four weeks, with most patients experiencing appetite reduction before significant fat loss occurs

turns out several are still offering compounded GLP-1s

Secondary endpoints included proportion of patients achieving 5%, 10%, 15%, and 20% weight loss, and improvements in metabolic, cardiovascular, and comorbidities after 12 months of follow-up

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A new report supports lower GLP-1 levels related to gut microbiome dysregulation @Cell_Metabolism

approximately 50% lower incidence of ovarian cancer