glp-1 agonists and anesthesia aGLP-1 receptor & anesthesia: ( practical perioperative approach you can actually use) receptor agonists (e.g., semaglutide, liraglutide, dulaglutide, tirzepatide) are now routine in patients presenting for procedures. For How should we approach patients

National Taiwan University researchers highlight the benefits of GLP-1 receptor agonists (GLP-1 RAs) in reducing mortality and severe cardiovascular and renal outcomes for diabetic patients with acute kidney disease (AKD)

Glucagon-like peptide-1 (GLP-1) is an incretin peptide hormone mainly secreted by enteroendocrine intestinal L-cells

A summary of the guidelines for perioperative management of GLP-1 RAs, GIP agonists, & SGLT2 inhibitors in adults.

Importantly, large-scale randomized trials, meta-analyses, and observational studies suggest that GLP-1RAs do not significantly increase AKI risk and may even confer renal benefits in high-risk populations

Some sub-analyses of large clinical trials suggest that GLP-1RA and sodium-glucose cotransporter 2 inhibitor combination therapy may provide more significant reductions in heart failure hospitalization and renal composite events than each alone

The results of a Phase II clinical trial have demonstrated significant weight reduction in overweight and obese adults