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Citrate is a natural compound in citrus fruits and some vegetables that directly inhibits kidney stone crystal formation

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An FDA approval decision is expected by the third quarter of 2025

Endogenous morphine, biosynthetically derived from dopamine, functions as a homeostatic modulator that stabilizes neuronal excitability via -opioid receptor signaling, with downstream coupling to nitric oxide production

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Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance