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The data is clear: your choice between tirzepatide and semaglutide should be based on your specific weight loss goals, tolerability, and metabolic needsnot on muscle preservation

doi: 10.1111/j.1748-1716.2010.02150.x [DOI] [PubMed] [Google Scholar] 53

GLP-1-induced delay can worsen nutritional deficits

(iv) suppression of high oxidative stress and systemic inflammation

This can increase the severity of SA through alterations upper airway inflammation and neuromuscular function, arousal mechanisms, and sleep architecture [53]

These drugs may be meant for long-term use, but as Ali pointed out, thats not in the cards for every patient
