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Detailed Category Analysis# Mechanism of Action# Pemvidutide : GLP-1/glucagon dual receptor agonist

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Rapid weight loss can often result in drastic changes to skin integrity

The combination of exenatide with the sodiumglucose co-transporter 2 (SGLT2) inhibitor, dapagliflozin, was investigated in the DURATION-8, phase III clinical trial which demonstrated a degree of synergy between the two agents, with improvements in short- and long-term glycaemia and weight loss exceeding either agent alone (144)

However, noticeable weight loss and the full effects on blood sugar levels may take up to 4-8 weeks to become evident

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