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Clinically, it is mainly used to treat T2DM and causes weight reduction when used in large doses (3mg/day) (83)

Recently, increasing evidence indicates that functional autophagy is required for synaptic functions, including neurotransmission and synaptic plasticity (75)

Lancet Diabetes Endocrinol 5:341354 Athauda D, Maclagan K, Skene SS, et al (2017) Exenatide once weekly versus placebo in Parkinsons disease: a randomised, double-blind, placebo-controlled trial

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[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Li W., Zhou Q., Cong Z., Yuan Q., Li W., Zhao F., Xu H.E., Zhao L.H., Yang D., Wang M.W

The response to GLP-1 analogues can vary from person to person