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Retatrutide and CJC/Ipa work through different biological systems

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Ji L., Gao L., Jiang H., et al., Safety and Efficacy of a GLP1 and Glucagon Receptor Dual Agonist Mazdutide (IBI362) 9 Mg and 10 Mg in Chinese Adults With Overweight or Obesity: A Randomised, PlaceboControlled, MultipleAscendingDose Phase 1b Trial, EClinicalMedicine 54 (2022): 101691, 10.1016/j.eclinm.2022.101691

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Peripherally, the main source of GLP-1 is the enteroendocrine GLP-1-producing cells in the small intestine and colon [27]
