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A medication that helps with weight loss AND reduces systemic inflammation AND improves cardiovascular markers addresses multiple aspects of the lupus burden simultaneously

2023;46(Supplement_1):S140-S157

Clinical trials have also revealed that these medications show promise for reducing severe risk factors associated with diabetes, such as heart disease

Liraglutide treatment also increased endothelial nitric oxide synthase (eNOS) and reduced intercellular adhesion molecule-1 (ICAM-1) expression in the aortic endothelium of atherogenic mice models ApoE / mice model [60]

Both are considering using it very early with their patients

Some evidence also points to direct protective effects on the heart and blood vessels independent of weight loss