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Personalized GLP-1 may also be a more cost-effective option for some patients

In a study of younger, middle-aged and older men and women, serum myostatin levels increased with age

The renal effects of arGLP1 in patients with CKD have been evaluated in other studies

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Another study in colonic-sensitized rat models demonstrated that exendin-4 treatment dose-dependently reduced visceral hypersensitivity by upregulating serotonin transporter (SERT) expression and downregulating tryptophan hydroxylase-1 (TPH-1) expression [57]