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Do GLP-1 supplements work even if I am not fasting

In the SURMOUNT-1 clinical trial, patients achieved significant weight reduction over 72 weeks, with average losses ranging from 15% to 21% of initial body weight depending on the dose

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The most consistent risk factor, however, is a small cup-to-disc ratio, referred to as a disc at risk, characterized by crowding of the optic nerve head with a resultant compartment-like syndrome of the nerve [36]

You can talk with your doctor to see if this might be the case for you