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Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

These findings shed new light on metformins mechanism of action in youth with type 2 diabetes, who have a high risk for metabolic complications and limited therapeutic options

Substance Use Disorders (SUD) Substance use interferes with treatment adherence, treatment response, and worsens illness outcomes in BD.[213] Bipolar spectrum disorders are common among SUDs, and often go unrecognized.[214,215] Management for BD and SUD may be initiated simultaneously, especially when withdrawal from substance use is deemed to contribute to mood instability.[216,217] The sparse available literature is summarized here.[213,216,217] For alcohol use disorder comorbid with BD, a randomized trial found that the combination of lithium and divalproex was more effective than lithium alone in reducing drinking frequency

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Awareness of the Pharmacists role was significantly higher among the counseled group (75%) compared to the non-counseled group (50%) (p = 0.0001), highlighting the importance of pharmacists in patient education