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Depending on how well hydrated you are, you could also show signs of dehydration like a fast heart rate, lower than normal blood pressure when you stand up, wrinkled skin, and dryness inside your mouth

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[DOI] [PubMed] [Google Scholar] 137.Nauck M.A., Friedrich N

In the SURMOUNT-5 head-to-head trial against semaglutide, tirzepatide at maximum dose produced 20.2% weight loss compared to semaglutide at 13.7%

Depending on which medication you are on, the injections are given twice daily, once daily or once weekly