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This triple-agonist approach works by[4,5]: Slowing stomach emptying after meals, helping you feel fuller longer Stabilizing blood sugar levels by stimulating insulin release Influencing glucagon signaling, which may increase energy expenditure Because many GLP-1 medications produce weight loss as a side effect, clinicians often prescribe them for weight management even in people without type 2 diabetes

Medicare still does not broadly cover obesity-only use today, although access is changing

The Express Scripts Prior Authorization Form PDF is a standardized document used to request prior authorization for medications through Express Scripts

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JAMA 2025;334:21862196