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Arun Sanyal, M.D., chief of the Division of Gastroenterology, Hepatology and Nutrition and director of the VCU Stravitz-Sanyal Institute for Liver Disease and Metabolic Health MASH affects around 15 million Americans, and currently there is only one FDA-approved treatment available, increasing the urgency for effective therapeutic options

For sustainable results, it should be integrated into a balanced plan that includes proper nutrition, exercise, and stress management

Current FDA Status (January 2026) Retatrutide is currently an investigational new drug (IND)

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Side Effects: What to Expect As with any medication, there are potential side effects associated with both Tirzepatide and Semaglutide

Huge uptick, the last three years in particular," with prescriptions filled "10 to 15 times a day