glp 1 gip dual agonist weight loss GIPR/GLP-1R therapies for diabetes and loss—chemistry, physiology, and clinical applications GLP-1 Medications for Weight Loss:

Novel perspectives on the link between obesity and cancer risk: from mechanisms to clinical implications

The brain pathway may be more significant than the endocrine route for the physiological effects of GLP-1, especially regarding insulin release, but the endocrine route becomes more pronounced with bigger meals and more L-cell activation (Deacon 2019)

Kohler et al., 2017)

Reduced reliance on conventional sugars is a practical benefit for patients using GLP-1 therapies who are working to modify their diet

Hypoglycemia: Especially when combined with other diabetes medications, leading to dangerously low blood sugar levels

Rapid weight loss, however, can also cause bone density loss