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GLP-1 RAs, such as tirzepatide and semaglutide, have become widely used to treat obesity and type 2 diabetes

Lipodystrophy presents through localized fat loss or gain that can modify how drugs are absorbed and how effective they are [45]

Semaglutide, developed by Novo Nordisk under the brand name Ozempic for type 2 diabetes, is administered as a once-weekly subcutaneous injection with a starting dose of 0.25 mg to a maximum dose of 2 mg per week

And I would expect that the clinical necessity of that will be really clear with these medications as people know, there are real side effects

The combined effect leads to improved glycaemic control and significant weight loss

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