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Perirenal fat thickness is significantly associated with the risk for development of chronic kidney disease in patients with diabetes

FDA labeling includes warnings about pancreatitis, gallbladder disease, kidney injury related to dehydration, serious allergic reactions, diabetic retinopathy complications in some patients with diabetes, and possible thyroid C-cell tumor risk based on animal studies

This duration-dependent relationship held up specifically in cardiovascular outcome trials, where the odds ratio reached 2.18 (95% CI: 1.36-3.49)

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