severe gas pain glp 1 GLP-1 nausea: How to handle GLP-1s' most common side GLP-1 Intolerance and Endoscopic Sleeve
Description
Nausea, constipation , and fatigue are the most commonly reported issues

GLP-1 therapiessuch as semaglutide and newer dual agonists like tirzepatidehave demonstrated substantial weight loss and metabolic benefits, far exceeding traditional therapies and supporting patients in diet and lifestyle changes

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Discuss with your provider whether continued escalation makes sense based on your specific trajectory

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Semaglutide Constipation: What Patients Should Expect Semaglutide constipation is commonly reported during early treatment or dose adjustments
