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PMCID: PMC11397063

It is because your biology was working against you

Suicidal behavior within 30 days before screening

The dual-receptor mechanism also appears to support improved blood-sugar regulation, lower triglycerides, and even better energy stability throughout the day

Other routes of administration (including inhaled and topical: dental-intracanal, dermal, intranasal, ophthalmological and perianal) are not prohibited when used within the manufacturers licensed doses and therapeutic indications

Collectively, these findings are consistent with the development of relative GLP-1 resistance acquired in the context of aging or HFD feeding
