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Moderately severe or severely symptomatic hyponatremia: rapid increase in serum sodium with IV hypertonic saline followed by cause-specific treatment for hyponatremia Nonsevere symptoms (usually chronic hyponatremia): slow correction of serum sodium with cause-specific treatment for hyponatremia (e.g., fluid restriction in SIADH)

Shorter treatment durations may result in less weight loss and a higher risk of weight regain

At the end of the 12-week lead-in period, participants achieved 6.9% (7.6 kg or 16.8 lbs.) mean weight loss
However, low blood sugar symptoms were reported more frequently when Ozempic was used together with other medications that can lower your blood sugar, such as insulin
