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Patients, meanwhile, are caught in the middle, hopeful for transformative benefits, but wary of affordability, side effects, and whether the early hype can translate into durable health outcomes

Tirzepatide works by activating two gut hormone receptors: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)

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"And when you reverse the fibrosis, that allows the body to start clearing out the scar tissue. Usually, with a 5% to 7% loss of body weight, patients can have a significant reduction in fat content, as much as 65%, Jensen said