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doi: 10.1111/febs.16638 63 HuynhTVDavisAAUlrichJDHoltzmanDM

This initial recognition step allows the peptides N-terminus to engage deep within the receptor TMD core, triggering a conformational change proximal to the intracellular region that results in G protein coupling and activation of the downstream signalling cascade 3,4,5,6,7

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