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The National Institute for Health and Care Excellence (NICE) defines heavy menstrual bleeding as excessive menstrual blood loss that interferes with a woman's physical, social, emotional, or material quality of life

While on treatment, appetite quiets and fullness lasts longer

And perhaps most importantly, maintaining lifestyle changes (diet and exercise) after stopping can help minimize how much weight returns

However, rapid weight loss, caloric restriction, gastrointestinal side effects, and blood glucose fluctuations may all influence emotional wellbeing

However, most people achieving 12-17% weight loss with Semaglutide experience significant health improvements and may not need to switch

These findings suggest that retatrutide may have a favourable impact on metabolic health, potentially offering additional benefits beyond weight loss