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This includes pancreatitis and kidney damage

Reduce dietary fat

doi: 10.2337/db09-1694 26 HoganAETobinAMAhernTCorriganMAGaoatsweGJacksonRet al

Most cases can be managed conservatively without discontinuing the medication

It peaks during the first 1 to 2 weeks after each dose escalation, then diminishes as the body adapts

Interestingly, the neural circuits responsible for the metabolic effects of GLP-1R agonism may be distinct from those mediating nausea or malaise ( Dosing schedule and route have also been identified a major factor affecting compliance with a single weekly injection achieving just over 10% lower risk of discontinuation (Weeda et al., 2021)