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We keep learning more about the array of beneficial impacts that GLP-1 drugs have on the brain, a new 1st rate review @Cell_Metabolism, including: the neuro-glial-vascular unit, including integrity of the blood brain barrier (Figure) protection of myelin sheath reducing

However, the reversed effect of semaglutide on cardiac hypertrophy was abolished by HCQ, which restored the activation of NLRP3 inflammasome suppressed by improved mitophagy

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Cardiovascular System: While the exact mechanisms are not fully elucidated, semaglutide appears to have direct and indirect effects on the cardiovascular system
