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Lower systemic bioavailability from nasal delivery would be expected to reduce the incidence and severity of these GI effects

However, there are not many CDMOs available with open capacity - most of them are going through expansions that will provide capacity in the next 1 to 2 years

Among those who stayed on treatment for the full 68 weeks, cagrilintide 2.4 mg delivered an average of about 12% body weight reduction , compared to 2.3% for placebo

GLP-1 is reported to exert important functions in the management of type 2 diabetes (T2D) and obesity, including regulation of glucose homeostasis, gastric motility and food intake

Administering the injection on the same day each week helps maintain consistent medication levels, which supports both effectiveness and tolerability

In fact, thats what it was originally designed for before doctors and patients realized just how effective it can be for weight loss, too