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This paper reviews the physiological, pharmacologic, and clinical foundations linking GLP-1 RA therapy to reproductive outcomes
At 12 months, weight loss persisted at around 4%, with variability between agents, most notably liraglutide
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Beyond these metabolic benefits, accumulating evidence indicates that GLP-1RAs exert immunomodulatory effects, including suppression of pro-inflammatory cytokines, enhancement of regulatory T-cell function, and improvements in adipose tissue and gut-derived immune signaling
