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More serious side effects you should seek immediate medical attention for include: Severe vomiting and diarrhea Severe pain in your abdomen The inability to have bowel movements or pass gas Jaundiced, or yellow tinted, skin How to Monitor Progress To have the best experience possible with GLP-1 medications its important that you track what you eat, any side effects, and how youre feeling so you can report back to your doctor

Circulating cytokines can cross the bloodbrain barrier and activate microglia, which subsequently release additional inflammatory mediators, including IL-1, IL-6, and TNF-

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Each agent is unique, however, and will likely differ in adverse effects

Exenatide, derived from Heloderma lizard venom, exhibits resistance to DPP-4 degradation with a half-life of approximately 24 h [68, 69], and its formulation in poly(lactic-co-glycolic acid) (PLGA) microspheres (Bydureon BCise ) enables once-weekly dosing by prolonging release kinetics [70]