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In summary, GLP-1 (and possibly GIP/GLP-1) receptor agonists could improve asthma outcomes through weight reduction, decreased airway inflammation and mucus secretion, decreased type 2 inflammation signaling, reduction in IL-4, 5, 13, and 33 secretion, reduced mast cell activity, as well as increases in surfactant production and smooth muscle relaxation [57]

The Accelerated Approval is based on part 1 of the ESSENCE trial that showed that at 72 weeks, 36.8% of people treated with Wegovy 2.4 mg achieved improvement in liver fibrosis with no worsening of steatohepatitis compared to 22.4% of individuals who received placebo

Kuylman of Warren Terzian LLP

Bydureon BCise (Exenatide): Whats it Approved For

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