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But from a neuropathology perspective, the evidence is thin

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Pharmacologic therapies, including glucagon-like peptide-1 receptor agonists and thyroid hormone receptor- agonists, improve histologic endpoints and fibrosis regression, although heterogeneity among clinical trials precludes direct comparison

Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted following nutrient intake, in response to elevated blood glucose levels, stimulating insulin secretion from pancreatic -cells and suppress glucagon secretion from pancreatic -cells