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Description
GLP-1 injection belong to GLP-1 receptor agonists (GLP-1 RAs), a class of synthetic drugs with a structure similar to natural GLP-1, but modified to prolong half-life and reduce dosing frequency
That means a 10 percent loss commonly produces a drop in the range of 0.5 to 1.0 percentage points, with larger absolute drops when starting A1C is higher
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In everyday life, you might stay on a GLP-1 long-term
They could have off-target negative health effects, and it will be years before we know if they have the same kind of positive effects on long-term heart and kidney health as semaglutide and tirzepatide. But there may also be unanticipated benefits beyond easier use
Type 2 diabetes mellitus and heart failure: A position statement from the Heart Failure Association of the European Society of Cardiology
