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Nevertheless, sulphasalazine has been demonstrated to be an effective treatment in cancer models, by inhibiting xCT to activate ferroptosis 232,233 and restore sensitivity to chemotherapy

Effects of Met supplementation on plasma metabolite levels in subacute aging mice The plasma metabolic profiles were analyzed using nuclear magnetic resonance (NMR) spectroscopy

Gel filtration was performed on a Sephadex G-100 column to reveal the enzyme's native molecular weight of approximately 50,000

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They also learned that excessive iron in oligodendrocytescells that support and insulate nerve fiberstriggers a type of cell death known as ferroptosis, possibly contributing to the formation of amyloid-beta plaques linked to Alzheimers

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