trump glp-1 announcement President announced the popular weight loss drugs would soon be more accessible to millions of Americans at a cost of only $50 per month. | Fox 5 DC White House launches discount drug

Why it matters: Lillys top rival, Novo Nordisk, also has two very successful GLP-1 drugs (Ozempic and Wegovy) and a third that is less popular, but still brings in over $1 billion in annual US sales (Rybelsus)

Its approval was preceded by the outcomes of five phase III trials, which are summarized in Tables 1 and 2, each of which compare tirzepatide at 5 mg, 10 mg, and 15 mg to other medications comparing similar clinical endpoints

Decreased risk of anxiety in diabetic patients receiving glucagonlike peptide1 receptor agonist: a nationwide, populationbased cohort study

Areas of controversy in neuroprogression in bipolar disorder

In leptin-deficient ob/ob mice, sitagliptin at 50 mg/kg daily for 4 weeks ameliorated weight gain, metabolic disorders, and steatosis in the liver as well as insulin sensitivity

Diabetes Care (2021) 44(Suppl 1):S12