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GLP-1 receptors help regulate insulin secretion, appetite suppression, and glucose balance

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The study compared the efficacy and safety of FDA-approved incretin-based therapies for weight management: tirzepatide, semaglutide, and liraglutide
Efpeglenatide A long-acting GLP-1 receptor agonist being developed for improved glycaemic control and weight reduction

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While peptide drugs have a wide range of therapeutic applications, their relatively short half-life has been a challenge, attributed to poor metabolic stability and a fluid dynamic radius below the glomerular filtration limit of the kidneys.
