214lbs => 69] (5months) glp1 med, diet, lots of exercise. : r/progresspics Man Loses 278 Lbs. Without" loading="eager" fetchpriority="high" decoding="async"/>
glp-1 before and after men M/38/6'1" [283lbs (-)> 214lbs => 69] (5months) glp1 med, diet, lots of exercise. : r/progresspics Man Loses 278 Lbs. Without
Description
(12) used Cre-lox technology to delete the gene encoding the GLP-1R specifically in the CNS (nestin- Cre Glp1r fl/fl mice) or in the peripheral nervous system ( Phox2b-Cre Glp1r fl/fl mice)
![glp-1 before and after men M/38/6'1" [283lbs (-)> 214lbs => 69] (5months) glp1 med, diet, lots of exercise. : r/progresspics Man Loses 278 Lbs. Without](https://people.com/thmb/AMl8Ax_u_BJIhe8OQMYe801hCyE=/1500x0/filters:no_upscale():max_bytes(150000):strip_icc():focal(999x0:1001x2)/brian-anderson-before-after-123025-5bb15f3499a2418e81c55e937a46feb2.jpg)
Most patients tolerate compounded tirzepatide well
One such breakthrough approach involves the use of GLP-1-based therapies, like Ozempic
![glp-1 before and after men M/38/6'1" [283lbs (-)> 214lbs => 69] (5months) glp1 med, diet, lots of exercise. : r/progresspics Man Loses 278 Lbs. Without](https://i.ytimg.com/vi/C-XN71Y97yA/hq720.jpg?sqp=-oaymwEhCK4FEIIDSFryq4qpAxMIARUAAAAAGAElAADIQj0AgKJD&rs=AOn4CLDrrjZbuspfzgBcjCBrzy-sq2jeDw)
If you are not comfortable abandoning fiber, here are two options that may give you the best of both worlds
![glp-1 before and after men M/38/6'1" [283lbs (-)> 214lbs => 69] (5months) glp1 med, diet, lots of exercise. : r/progresspics Man Loses 278 Lbs. Without](https://www.zmedclinic.com/wp-content/uploads/2025/05/2-1.jpg)
Engagement groups (high vs
![glp-1 before and after men M/38/6'1" [283lbs (-)> 214lbs => 69] (5months) glp1 med, diet, lots of exercise. : r/progresspics Man Loses 278 Lbs. Without](https://lirp.cdn-website.com/9223eb51/dms3rep/multi/opt/2-03d9e3fb-640w.png)
Months 7+ (5-10 mg maintenance): $400-$450/month
![glp-1 before and after men M/38/6'1" [283lbs (-)> 214lbs => 69] (5months) glp1 med, diet, lots of exercise. : r/progresspics Man Loses 278 Lbs. Without](https://blueskymd.com/wp-content/uploads/2025/08/David-943x1024.png)