reddit semaglutide vs tirzepatide then : r/OzempicForWeightLoss is tirzepatide better than semaglutide
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It was soon demonstrated that leaks in the blood barrier notably in the area postrema, the subfornical organ and the median eminence would not only allow entry of GLP-1 into these regions of the brain (87), but there was also dense receptor expression at these sites suggesting peripheral GLP-1 might also have actions on the brain (80), and in 1998 it was demonstrated that peripheral intravenous infusions of physiological amounts of GLP-1 would lead to decreased appetite and inhibition of food intake (88)

Combination therapy is not new

Heres what to focus on: Prioritize lean protein

What Are GLP-1RAs

Pharmacotherapy 1996;16:971-85
