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A budget-impact analysis was conducted to understand the total direct medical cost tradeoff associated with switching patients from sitagliptin 100 mg to oral semaglutide 14 mg in second-line T2DM from a healthcare sector perspective

Wegovy (Semaglutide Injection) Approved by the FDA, Wegovy is a semaglutide injection for adults with a BMI of 30 or higher, or 27 or higher with weight-related conditions

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The extent to which this occurs with Retatrutide depends heavily on protein intake and resistance training during the protocol

This represents one of the most significant documented pharmaceutical weight loss interventions, with sustained reductions even after 2 years of continuous use in follow-up studies