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The Lipitor Case: The Cliff as a Historical Fact Pfizers handling of atorvastatins patent expiry remains the canonical case study because the cliff hit with unusual severity and because Pfizers defensive strategies were more visible than most

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It is being studied in clinical trials for obesity, overweight with weight-related conditions, type 2 diabetes, knee osteoarthritis pain, moderate-to-severe obstructive sleep apnea, chronic low back pain, cardiovascular and renal outcomes, and metabolic dysfunction-associated steatotic liver disease

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5153 Notably, of the different HF phenotypes, HFpEF is associated with the worst HRQoL, whereas among HFpEF patients, the worst HRQoL had been shown in a subgroup with the highest BMI, a higher proportion of at least Grade 2 obesity and T2D